OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN6

OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN6

Abstract Background CCN6 is a matricellular protein that critically regulates the tumourigenesis and progression of breast cancer. Although the tumour‐suppressive function of CCN6 has been extensively studied, molecular mechanisms regulating protein levels of CCN6 remain largely unclear. This study...

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Bibliographic Details
Main Authors: Ying Zhao, Jing Ruan, Zhongding Li, Xian Su, Kangmin Chen, Yimin Lin, Yuepiao Cai, Peng Wang, Baohua Liu, Dirk Schlüter, Guang Liang, Xu Wang
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Clinical and Translational Medicine
Subjects:
breast cancer
CCN6
OTUB1
protein degradation
ubiquitination
Online Access:https://doi.org/10.1002/ctm2.1385

Internet

https://doi.org/10.1002/ctm2.1385

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