Upregulation of extracellular proteins in a mouse model of Alzheimer’s disease

Abstract Various risk factors of Alzheimer’s disease (AD) are known, such as advanced age, possession of certain genetic variants, accumulation of toxic amyloid-β (Aβ) peptides, and unhealthy lifestyle. An estimate of heritability of AD ranges from 0.13 to 0.25, indicating that its phenotypic variat...

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Bibliographic Details
Main Authors: Sangkyu Kim, Jessica Fuselier, Anna Latoff, Justin Manges, S. Michal Jazwinski, Andrea Zsombok
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33677-z