A trimeric spike-based COVID-19 vaccine candidate induces broad neutralization against SARS-CoV-2 variants

A trimeric spike-based COVID-19 vaccine candidate induces broad neutralization against SARS-CoV-2 variants

COVID-19 pandemic caused by SARS-CoV-2 infection has an impact on global public health and social economy. The emerging immune escape of SARS-CoV-2 variants pose great challenges to the development of vaccines based on original strains. The development of second-generation COVID-19 vaccines to induc...

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Bibliographic Details
Main Authors: Feixia Gao, Mei Zheng, Jiangfeng Fan, Yahong Ding, Xueying Liu, Min Zhang, Xin Zhang, Jinrong Dong, Xu Zhou, Jian Luo, Xiuling Li
Format: Article
Language:English
Published: Taylor & Francis Group 2023-01-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
sars-cov-2
vaccine
s-trimer protein
cpg
aluminum hydroxide adjuvant
cross-neutralization
Online Access:http://dx.doi.org/10.1080/21645515.2023.2186110

Internet

http://dx.doi.org/10.1080/21645515.2023.2186110

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