Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells

<p>Abstract</p> <p>Background</p> <p><it>N</it>-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a synthetic retinoid with potent pro-apoptotic activity against several types of cancer, but little is known regarding mechanisms leading to chemoresistance....

Full description

Bibliographic Details
Main Authors: Hannun Yusuf A, Pérez-Yarza Gorka, Boyano María, Idkowiak-Baldys Jolanta K, Apraiz Aintzane, Asumendi Aintzane
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/477