Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds
ABSTRACT Collateral sensitivity (CS) is an evolutionary trade-off by which acquisition of resistance to an antibiotic leads to increased susceptibility to another. This Achilles’ heel of antibiotic resistance could be exploited to design evolution-based strategies for treating bacterial infections....
| Main Authors: | , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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American Society for Microbiology
2023-02-01
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| 丛编: | Microbiology Spectrum |
| 主题: | |
| 在线阅读: | https://journals.asm.org/doi/10.1128/spectrum.02276-22 |