Validation of In Vitro Trained Transcriptomic Radiosensitivity Signatures in Clinical Cohorts

Transcriptomic personalisation of radiation therapy has gained considerable interest in recent years. However, independent model testing on in vitro data has shown poor performance. In this work, we assess the reproducibility in clinical applications of radiosensitivity signatures. Agreement between...

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Bibliographic Details
Main Authors: John D. O’Connor, Ian M. Overton, Stephen J. McMahon
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/13/3504