Proteolytic Activation of the Epithelial Sodium Channel (ENaC): Its Mechanisms and Implications

Proteolytic Activation of the Epithelial Sodium Channel (ENaC): Its Mechanisms and Implications

Epithelial sodium channel (ENaC) are integral to maintaining salt and water homeostasis in various biological tissues, including the kidney, lung, and colon. They enable the selective reabsorption of sodium ions, which is a process critical for controlling blood pressure, electrolyte balance, and ov...

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Bibliographic Details
Main Authors: Mohammed Aufy, Ahmed M. Hussein, Tamara Stojanovic, Christian R. Studenik, Mohamed H. Kotob
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
ENaC
ENaC activation
proteases
epithelial sodium channel
furin
plasmin
Online Access:https://www.mdpi.com/1422-0067/24/24/17563

Internet

https://www.mdpi.com/1422-0067/24/24/17563

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