Fusobacterium nucleatum-triggered purine metabolic reprogramming drives tumorigenesis in head and neck carcinoma

Fusobacterium nucleatum-triggered purine metabolic reprogramming drives tumorigenesis in head and neck carcinoma

Abstract Background Fusobacterium nucleatum (F. nucleatum) is a vital pro-oncogenic bacterium. Our previous study revealed that a high abundance of F. nucleatum in head and neck squamous cell carcinoma (HNSCC) is correlated with poor patient prognosis. However, the impact of F. nucleatum on metaboli...

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Bibliographic Details
Main Authors: Feiran Li, Huiying Huang, Jing Xu, Lei Tao, Liang Zhou, Chiyao Hsueh, Hongli Gong, Ming Zhang
Format: Article
Language:English
Published: Springer 2023-07-01
Series:Discover Oncology
Subjects:
Head and neck carcinoma
Fusobacterium nucleatum
Metabolic reprogramming
Purine metabolic pathway
Prognosis
Online Access:https://doi.org/10.1007/s12672-023-00727-x

Internet

https://doi.org/10.1007/s12672-023-00727-x

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