Piperacillin/Tazobactam and Meropenem Use Increases the Risks for Acute Graft Rejection Following First Kidney Transplantation

Piperacillin/Tazobactam and Meropenem Use Increases the Risks for Acute Graft Rejection Following First Kidney Transplantation

Many broad-spectrum antibiotics (BSA) alter the intestinal microbiome that regulates adaptive immune responses. We hypothesized that BSA use before and early after kidney transplant may affect acute graft rejection (AGR). We carried out a retrospective cohort study on all patients who underwent kidn...

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Bibliographic Details
Main Authors: Dayana Nasr, Mahmoudreza Moein, Stephanie Niforatos, Sandy Nasr, Mulham Ombada, Farzam Khokhar, Myera Shahnawaz, Bhavya Poudyal, Maroun Bou Zerdan, Dibyendu Dutta, Reza F. Saidi, Seah H. Lim
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
broad-spectrum antibiotics
kidney transplant
acute graft rejection
obligate anaerobic organisms
risk factors
Online Access:https://www.mdpi.com/2077-0383/11/10/2726

Internet

https://www.mdpi.com/2077-0383/11/10/2726

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