Endoplasmic Stress Inhibition during Oocyte Maturation Improves Preimplantation Development of Cloned Pig Embryos
Mitochondrial dysfunction is found in oocytes and transmitted to offspring due to maternal obesity. Treatment of obese mothers with endoplasmic reticulum (ER) stress inhibitors such as salubrinal (SAL) can reverse the mitochondrial dysfunction and result in normal embryonic development. Pig oocytes...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Animal Reproduction and Biotechnology
2017-12-01
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Series: | Journal of Animal Reproduction and Biotechnology |
Subjects: | |
Online Access: | http://www.e-jarb.org/journal/view.html?uid=26&vmd=Full |