Endoplasmic Stress Inhibition during Oocyte Maturation Improves Preimplantation Development of Cloned Pig Embryos

Endoplasmic Stress Inhibition during Oocyte Maturation Improves Preimplantation Development of Cloned Pig Embryos

Mitochondrial dysfunction is found in oocytes and transmitted to offspring due to maternal obesity. Treatment of obese mothers with endoplasmic reticulum (ER) stress inhibitors such as salubrinal (SAL) can reverse the mitochondrial dysfunction and result in normal embryonic development. Pig oocytes...

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Bibliographic Details
Main Authors: Fazle Elahi, Hyeji Shin, Joohyeong Lee, Eunsong Lee
Format: Article
Language:English
Published: The Korean Society of Animal Reproduction and Biotechnology 2017-12-01
Series:Journal of Animal Reproduction and Biotechnology
Subjects:
oocyte maturation
endoplasmic reticulum stress
embryonic development
pig
Online Access:http://www.e-jarb.org/journal/view.html?uid=26&vmd=Full

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