Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway

Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway

BackgroundInsulin resistance (IR), which is affected by dietary factors, is the main pathology underlying of gestational diabetes mellitus (GDM). Fructose (Fru), a sugar found in fruits, honey, and food sweeteners, has been reported to induce IR and inflammation. This study explored the effects and...

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Bibliographic Details
Main Authors: Yao Liu, Yuanhuan Wei, Lanlan Wu, Xiaoping Lin, Ruifang Sun, Hengying Chen, Siwen Shen, Guifang Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Nutrition
Subjects:
gestational diabetes mellitus
insulin resistance
fructose
nucleotide-binding domain-like receptor protein 3 inflammasome
nuclear factor-κappa B
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.839174/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.839174/full

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