Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer

<p>Abstract</p> <p>Background</p> <p>Interleukin-13 Receptor α2 (IL-13Rα2) is a tumor-associated antigen and target for cancer therapy. Since IL-13Rα2 is heterogeneously overexpressed in a variety of human cancers, it would be highly desirable to uniformly upregulate IL...

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Bibliographic Details
Main Authors: Puri Raj K, Joshi Bharat H, Fujisawa Toshio
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/37