The Crohn's disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells.

Crohn's disease (CD) is a debilitating inflammatory bowel disease (IBD) that arises from chronic inflammation in the gastrointestinal tract. Genome-wide association studies (GWAS) have identified over 200 single nucleotide polymorphisms (SNPs) that are associated with a predisposition for devel...

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Bibliographic Details
Main Authors: Stephen M Matthews, Melanie A Eshelman, Arthur S Berg, Walter A Koltun, Gregory S Yochum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212850