Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1

Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1

Summary: Obstructive sleep apnea (OSA) is a common sleep disordered breathing diseases that characterized by chronic intermittent hypoxia (CIH). This work aimed to explore the role of circ-CIMIRC in CIH-induced myocardial injury. CIH aggravated myocardial tissue damage in rats. Circ_CIMIRC overexpre...

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Bibliographic Details
Main Authors: Runhua Wu, Fengsheng Xu, Jingyi Li, Feng Wang, Naijie Chen, Xiaoting Wang, Qin Chen
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Molecular biology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224002037

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224002037

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