Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage

Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage

Abstract Background Subarachnoid hemorrhage (SAH) is a life -threatening cerebrovascular disease, where early brain injury (EBI) stands as a primary contributor to mortality and unfavorable patient outcomes. Neuronal ferroptosis emerges as a key pathological mechanism underlying EBI in SAH. Targetin...

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Bibliographic Details
Main Authors: Yong Li, Xinyi Zhu, Wei Xiong, Qingyu Zhao, Youdong Zhou, Yujia Guo, Baohui Liu, Mingchang Li, Qianxue Chen, Xiaobing Jiang, Yangzhi Qi, Qingsong Ye, Gang Deng
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Nanobiotechnology
Subjects:
Subarachnoid hemorrhage
Early brain injury
Ferroptosis
Ursolic acid
Self-assembled nanoparticles
Online Access:https://doi.org/10.1186/s12951-024-02866-x

Internet

https://doi.org/10.1186/s12951-024-02866-x

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