Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice

Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice

Summary: Multiple genome-wide association studies (GWAS) have identified specific genetic variants in the coiled-coil domain containing 92 (CCDC92) locus that is associated with obesity and type 2 diabetes in humans. However, the biological function of CCDC92 in obesity and insulin resistance remain...

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Bibliographic Details
Main Authors: Lu Ren, Wa Du, Dan Song, Haocheng Lu, Milton H. Hamblin, Chenran Wang, Chunying Du, Guo-Chang Fan, Richard C. Becker, Yanbo Fan
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Cell biology
Cellular physiology
Pathophysiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222020429

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http://www.sciencedirect.com/science/article/pii/S2589004222020429

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