MOV10 and FMRP Regulate AGO2 Association with MicroRNA Recognition Elements

Summary: The fragile X mental retardation protein FMRP regulates translation of its bound mRNAs through incompletely defined mechanisms. FMRP has been linked to the microRNA pathway, and we show here that it associates with the RNA helicase MOV10, also associated with the microRNA pathway. FMRP asso...

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Bibliographic Details
Main Authors: Phillip J. Kenny, Hongjun Zhou, Miri Kim, Geena Skariah, Radhika S. Khetani, Jenny Drnevich, Mary Luz Arcila, Kenneth S. Kosik, Stephanie Ceman
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714009231