Effect of Adenomatous Polyposis Coli Loss on Tumorigenic Potential in Pancreatic Ductal Adenocarcinoma

Effect of Adenomatous Polyposis Coli Loss on Tumorigenic Potential in Pancreatic Ductal Adenocarcinoma

Loss of the <i>Adenomatous Polyposis Coli</i> (<i>APC</i>) tumor suppressor in colorectal cancer elicits rapid signaling through the Wnt/&#946;-catenin signaling pathway. In contrast to this well-established role of APC, recent studies from our laboratory demonstrated tha...

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Bibliographic Details
Main Authors: Jennifer M. Cole, Kaitlyn Simmons, Jenifer R. Prosperi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
PDAC
APC
proliferation
migration
gemcitabine
Online Access:https://www.mdpi.com/2073-4409/8/9/1084

Internet

https://www.mdpi.com/2073-4409/8/9/1084

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