Hyaluronic Acid Suppresses the Expression of Metalloproteinases in Osteoarthritic Cartilage Stimulated Simultaneously by Interleukin 1β and Mechanical Load.

Hyaluronic Acid Suppresses the Expression of Metalloproteinases in Osteoarthritic Cartilage Stimulated Simultaneously by Interleukin 1β and Mechanical Load.

In patients with osteoarthritis (OA), intraarticular injection of hyaluronic acid (HA) frequently results in reduced pain and improved function for prolonged periods of time, i.e. more than 6 months. However, the mechanisms underlying these effects are not fully understood. Our underlying hypothesis...

Full description

Bibliographic Details
Main Authors: Florian Pohlig, Florian Guell, Ulrich Lenze, Florian W Lenze, Heinrich M L Mühlhofer, Johannes Schauwecker, Andreas Toepfer, Philipp Mayer-Kuckuk, Rüdiger von Eisenhart-Rothe, Rainer Burgkart, Gian M Salzmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4774918?pdf=render

Internet

http://europepmc.org/articles/PMC4774918?pdf=render

Similar Items