Toxo: a library for calculating penetrance tables of high-order epistasis models

Abstract Background Epistasis is defined as the interaction between different genes when expressing a specific phenotype. The most common way to characterize an epistatic relationship is using a penetrance table, which contains the probability of expressing the phenotype under study given a particul...

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Bibliographic Details
Main Authors: Christian Ponte-Fernández, Jorge González-Domínguez, Antonio Carvajal-Rodríguez, María J. Martín
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3456-3