p19Arf sensitizes B16 melanoma cells to interferon-β delivered via mesenchymal stem cells in vitro

The immune stimulatory and anti-neoplastic functions of type I interferon have long been applied for the treatment of melanoma. However, the systemic application of high levels of this recombinant protein is often met with toxicity. An approach that provides localized, yet transient, production of t...

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Bibliographic Details
Main Authors: R.C. Da-Costa, I.L. Vieira, A. Hunger, R.E. Tamura, B.E. Strauss
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2020-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000300601&tlng=en