Interleukin-3-Receptor-α in Triple-Negative Breast Cancer (TNBC): An Additional Novel Biomarker of TNBC Aggressiveness and a Therapeutic Target

Interleukin-3-Receptor-α in Triple-Negative Breast Cancer (TNBC): An Additional Novel Biomarker of TNBC Aggressiveness and a Therapeutic Target

Tumour molecular annotation is mandatory for biomarker discovery and personalised approaches, particularly in triple-negative breast cancer (TNBC) lacking effective treatment options. In this study, the interleukin-3 receptor α (IL-3Rα) was investigated as a prognostic biomarker and therapeutic targ...

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Bibliographic Details
Main Authors: Malvina Koni, Isabella Castellano, Emilio Venturelli, Alessandro Sarcinella, Tatiana Lopatina, Cristina Grange, Massimo Cedrino, Saveria Femminò, Paolo Cossu-Rocca, Sandra Orrù, Fabrizio D’Ascenzo, Ilaria Cotellessa, Cristian Tampieri, Carla Debernardi, Giovanni Cugliari, Giuseppe Matullo, Giovanni Camussi, Maria Rosaria De Miglio, Maria Felice Brizzi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
interleukin-3/interleukin-3 receptor α
triple-negative breast cancer
vascular mimicry
programmed cell death-ligand 1
Online Access:https://www.mdpi.com/2072-6694/14/16/3918

Internet

https://www.mdpi.com/2072-6694/14/16/3918

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