ANGIOTENSIN AT1 - α2C-ADRENOCEPTOR INTERACTION DISTURBS α2A-AUTO-INHIBITION OF CATECHOLAMINE RELEASEIN HYPERTENSIVE RATS
α2-adrenoceptors (AR) lower central sympathetic output and peripheral catecholamine release, and thus may prevent sympathetic hyperactivity and hypertension. α2AR also influence vascular tension. These α2AR are malfunctioning in spontaneously hypertensive rats (SHR). Here I tested if an interaction...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-06-01
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Series: | Frontiers in Neurology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00070/full |