Male hormones activate EphA2 to facilitate Kaposi's sarcoma-associated herpesvirus infection: Implications for gender disparity in Kaposi's sarcoma.

There is increasing consensus that males are more vulnerable than females to infection by several pathogens. However, the underlying mechanism needs further investigation. Here, it was showed that knockdown of androgen receptor (AR) expression or pre-treatment with 5α-dihydrotestosterone, the AR ago...

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Bibliographic Details
Main Authors: Xing Wang, Zhe Zou, Zhaohui Deng, Deguang Liang, Xin Zhou, Rui Sun, Ke Lan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5619820?pdf=render