Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D3 analog, pefcalcitol

Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D3 analog, pefcalcitol

Abstract Background Pefcalcitol, an analog of vitamin D3 (VD3), is an anti-psoriatic drug candidate that is designed to achieve much higher pharmacological effects, such as keratinocyte differentiation, than those of VD3, with fewer side effects. Genotoxicity of the compound was evaluated in a rat s...

Full description

Bibliographic Details
Main Authors: Akira Takeiri, Kenji Tanaka, Asako Harada, Kaori Matsuzaki, Mariko Yano, Shigeki Motoyama, Chie Katoh, Masayuki Mishima
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Genes and Environment
Subjects:
Pefcalcitol
Vitamin D3
Micronucleus
Skin
Rat
Keratohyalin granule
Online Access:http://link.springer.com/article/10.1186/s41021-017-0077-9

Internet

http://link.springer.com/article/10.1186/s41021-017-0077-9

Similar Items