Polycation-π interactions are a driving force for molecular recognition by an intrinsically disordered oncoprotein family.

Molecular recognition by intrinsically disordered proteins (IDPs) commonly involves specific localized contacts and target-induced disorder to order transitions. However, some IDPs remain disordered in the bound state, a phenomenon coined "fuzziness", often characterized by IDP polyvalency...

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Bibliographic Details
Main Authors: Jianhui Song, Sheung Chun Ng, Peter Tompa, Kevin A W Lee, Hue Sun Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086122/pdf/?tool=EBI