Natural Antioxidant Control of Neuropathic Pain—Exploring the Role of Mitochondrial SIRT3 Pathway

Natural Antioxidant Control of Neuropathic Pain—Exploring the Role of Mitochondrial SIRT3 Pathway

Neuropathic pain is a chronic painful disease. Data have shown that reactive oxygen species (ROS) are implicated in chronic pain. Particularly, the enhanced ROS production alters the mitochondrial genome and proteome through the accumulation of lipid peroxidation products, such as 4-hydroxynonenal (...

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Bibliographic Details
Main Authors: Sara Ilari, Luigino Antonio Giancotti, Filomena Lauro, Micaela Gliozzi, Valentina Malafoglia, Ernesto Palma, Marco Tafani, Matteo Antonio Russo, Carlo Tomino, Massimo Fini, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
neuropathic pain
natural antioxidants
polyphenols
sirtuin 3
mitochondria
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/9/11/1103

Internet

https://www.mdpi.com/2076-3921/9/11/1103

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