Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolites

Abstract Given the complex exposures from both exogenous and endogenous sources that an individual experiences during life, exposome-wide association studies that interrogate levels of small molecules in biospecimens have been proposed for discovering causes of chronic diseases. We conducted a study...

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Bibliographic Details
Main Authors: Vincent Bessonneau, Roy R. Gerona, Jessica Trowbridge, Rachel Grashow, Thomas Lin, Heather Buren, Rachel Morello-Frosch, Ruthann A. Rudel
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87070-9