Immunization with Live-Attenuated RHΔ<i>had2a</i> Strain Confers Partial Protective Immunity against Acute and Chronic Infection of <i>Toxoplasma gondii</i> in Mice

Immunization with Live-Attenuated RHΔ<i>had2a</i> Strain Confers Partial Protective Immunity against Acute and Chronic Infection of <i>Toxoplasma gondii</i> in Mice

Toxoplasmosis caused by <i>Toxoplasma gondii</i> is an important zoonosis of human and animal health significance. Current chemical therapeutics have side effects, and no commercially available vaccine is licensed for the prevention of toxoplasmosis in humans and most animals. Developing...

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Bibliographic Details
Main Authors: Hai-Sheng Zhang, Hui Cao, Chen-Xu Li, Zhi-Wei Zhang, Meng Wang, Xing-Quan Zhu, Xiao-Nan Zheng
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pathogens
Subjects:
<i>Toxoplasma gondii</i>
toxoplasmosis
HAD phosphatase
CRISPR-Cas9
live-attenuated strain
vaccine
Online Access:https://www.mdpi.com/2076-0817/13/2/121

Internet

https://www.mdpi.com/2076-0817/13/2/121

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