CAR-T cell therapy: cell reprogramming to combat malignant neoplasms

CAR-T cell therapy: cell reprogramming to combat malignant neoplasms

The CAR-T cells are lymphocytes genetically modified to recognize a broader spectrum of cell surface antigens. In addition, they attack malignant tumor cells, which express these antigens, by activating cytoplasmic co-stimulation, cytokine secretion, tumor cell cytolysis and T cell proliferation. Th...

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Bibliographic Details
Main Authors: Soares, José Eduardo Palacio, Guerra, Lorenzo Alvarenga, Rezende Júnior, Ronaldo, Parreiras, Fernanda Cardoso
Format: Article
Language:English
Published: Associação Médica de Minas Gerais 2022-08-01
Series:Revista Médica de Minas Gerais
Subjects:
car-t cell therapy
neoplasms
immunotherapy
Online Access:http://www.rmmg.org/artigo/detalhes/3927

Internet

http://www.rmmg.org/artigo/detalhes/3927

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