Cannabidiol Downregulates Myocardial de Novo Ceramide Synthesis Pathway in a Rat Model of High-Fat Diet-Induced Obesity

It is known that metabolic disturbances, including obesity, predispose to an increased incidence of cardiovascular diseases. Elevated consumption of dietary fat results in intramyocardial accumulation of lipids and their biologically active derivatives, which can disrupt the contractile function of...

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Bibliographic Details
Main Authors: Tomasz Charytoniuk, Klaudia Sztolsztener, Patrycja Bielawiec, Adrian Chabowski, Karolina Konstantynowicz-Nowicka, Ewa Harasim-Symbor
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/4/2232