The chemotherapeutic drug methotrexate selects for antibiotic resistance

The chemotherapeutic drug methotrexate selects for antibiotic resistance

Background: Understanding drivers of antibiotic resistance evolution is fundamental for designing optimal treatment strategies and interventions to reduce the spread of antibiotic resistance. Various cytotoxic drugs used in cancer chemotherapy have antibacterial properties, but how bacterial populat...

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Bibliographic Details
Main Authors: Jónína S. Guðmundsdóttir, Elizabeth G.A. Fredheim, Catharina I.M. Koumans, Joachim Hegstad, Po-Cheng Tang, Dan I. Andersson, Ørjan Samuelsen, Pål J. Johnsen
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:EBioMedicine
Subjects:
Chemotherapeutic drugs
E. coli
Antibiotic resistance
Methotrexate
Resistance evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421005363

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http://www.sciencedirect.com/science/article/pii/S2352396421005363

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