An mTORC1‐Dependent Mouse Model for Cardiac Sarcoidosis

An mTORC1‐Dependent Mouse Model for Cardiac Sarcoidosis

Background Sarcoidosis is an inflammatory, granulomatous disease of unknown cause affecting multiple organs, including the heart. Untreated, unresolved granulomatous inflammation can lead to cardiac fibrosis, arrhythmias, and eventually heart failure. Here we characterize the cardiac phenotype of mi...

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Bibliographic Details
Main Authors: Carlos Bueno‐Beti, Clarice X. Lim, Alexandros Protonotarios, Petra Lujza Szabo, Joseph Westaby, Mario Mazic, Mary N. Sheppard, Elijah Behr, Ouafa Hamza, Attila Kiss, Bruno K. Podesser, Markus Hengstschläger, Thomas Weichhart, Angeliki Asimaki
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac sarcoidosis
fibrosis
heart
mouse model
mTORC1
sarcoidosis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.030478

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https://www.ahajournals.org/doi/10.1161/JAHA.123.030478

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