Novel Therapeutic Target Critical for SARS-CoV-2 Infectivity and Induction of the Cytokine Release Syndrome

We discovered a novel therapeutic target critical for SARS-CoV-2, cellular infectivity and the induction of the cytokine release syndrome. Here, we show that the mammalian enzyme neuraminidase-1 (Neu-1) is part of a highly conserved signaling platform that regulates the dimerization and activation o...

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Bibliographic Details
Main Authors: William W. Harless, Beth Lewis, Bessi Qorri, Samar Abdulkhalek, Myron R. Szewczuk
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/9/1332