Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome

Cranial sutures separate the skull bones and house stem cells for bone growth and repair. In Saethre-Chotzen syndrome, mutations in TCF12 or TWIST1 ablate a specific suture, the coronal. This suture forms at a neural-crest/mesoderm interface in mammals and a mesoderm/mesoderm interface in zebrafish....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Camilla S Teng, Man-chun Ting, D'Juan T Farmer, Mia Brockop, Robert E Maxson, J Gage Crump
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: eLife Sciences Publications Ltd 2018-10-01
Цуврал:eLife
Нөхцлүүд:
Онлайн хандалт:https://elifesciences.org/articles/37024