Triterpenic Acids as Non-Competitive α-Glucosidase Inhibitors from <i>Boswellia elongata</i> with Structure-Activity Relationship: In Vitro and In Silico Studies

Triterpenic Acids as Non-Competitive α-Glucosidase Inhibitors from <i>Boswellia elongata</i> with Structure-Activity Relationship: In Vitro and In Silico Studies

Fourteen triterpene acids, viz., three tirucallane-type (<b>1</b>–<b>3</b>), eight ursane-type (<b>4</b>–<b>11</b>), two oleanane-type (<b>12</b>, <b>13</b>) and one lupane type (<b>21</b>), along with boswellic alde...

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Bibliographic Details
Main Authors: Najeeb Ur Rehman, Sobia Ahsan Halim, Mohammed Al-Azri, Majid Khan, Ajmal Khan, Kashif Rafiq, Ahmed Al-Rawahi, Rene Csuk, Ahmed Al-Harrasi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
<i>Boswellia elongata</i>
triterpene acids
α-glucosidase inhibitors
NMR spectroscopy
kinetics study
homology modeling
Online Access:https://www.mdpi.com/2218-273X/10/5/751

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https://www.mdpi.com/2218-273X/10/5/751

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