Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber

Summary: Emerging evidence suggests that neuronal signaling is important for oligodendrocyte myelination; however, the necessity of this signaling during development is unclear. By eliminating dynamic neuronal signaling along the developing optic nerve, we find that oligodendrocyte differentiation i...

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Bibliographic Details
Main Authors: Sonia R. Mayoral, Ainhoa Etxeberria, Yun-An A. Shen, Jonah R. Chan
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718314979