Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model

Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model

Abstract Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective breeding or other strategies as it is done for classical scrapie outbreaks. Its spontaneo...

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Bibliographic Details
Main Authors: Enric Vidal, Manuel A. Sánchez-Martín, Hasier Eraña, Sonia Pérez Lázaro, Miguel A. Pérez-Castro, Alicia Otero, Jorge M. Charco, Belén Marín, Rafael López-Moreno, Carlos M. Díaz-Domínguez, Mariví Geijo, Montserrat Ordóñez, Guillermo Cantero, Michele di Bari, Nuria L. Lorenzo, Laura Pirisinu, Claudia d’Agostino, Juan María Torres, Vincent Béringue, Glenn Telling, Juan J. Badiola, Martí Pumarola, Rosa Bolea, Romolo Nonno, Jesús R. Requena, Joaquín Castilla
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Acta Neuropathologica Communications
Subjects:
Atypical
Scrapie
Spontaneous
Prion disease
Isoleucine
Online Access:https://doi.org/10.1186/s40478-022-01477-7

Internet

https://doi.org/10.1186/s40478-022-01477-7

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