Long-lived plasma cells in autoimmunity: lessons from B-cell depleting therapies.

A large number of autoimmune diseases are treated with rituximab, an antibody against CD20 that depletes most of the B cells in the organism. The response to this treatment depends largely on the disease and the type of lymphoid cells involved in the autoimmune process. We recently reported that B-c...

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Bibliographic Details
Main Authors: Matthieu eMahévas, Marc eMichel, Jean-Claude eWeill, Claude-Agnes eReynaud
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00494/full