PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing

The PIEZO1 channel and the PECAM1 cell adhesion molecule interact and PIEZO1 cooperates with PECAM1 and CDH5 cell junctions during mechanical stress.

Bibliographic Details
Main Authors: Eulashini Chuntharpursat-Bon, Oleksandr V. Povstyan, Melanie J. Ludlow, David J. Carrier, Marjolaine Debant, Jian Shi, Hannah J. Gaunt, Claudia C. Bauer, Alistair Curd, T. Simon Futers, Paul D. Baxter, Michelle Peckham, Stephen P. Muench, Antony Adamson, Neil Humphreys, Sarka Tumova, Robin S. Bon, Richard Cubbon, Laeticia Lichtenstein, David J. Beech
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04706-4