Overcoming T-cell exhaustion in glioblastoma: A narrative review

Overcoming T-cell exhaustion in glioblastoma: A narrative review

Immunotherapy is typically ineffective against glioblastoma (GBM) due to inherent and adaptive resistance. Initial immunotherapy results for GBM have been disappointing. In this regard, T-cell exhaustion is a major barrier to successful treatment. The recognition of exhausted CD8+ T cell (Tex) pedig...

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Bibliographic Details
Main Authors: Xuya Wang, Xisen Wang, Jiabo Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Glioma
Subjects:
brain tumor
glioblastoma
immunotherapy
t-cell exhaustion
tumor microenvironment
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2022;volume=5;issue=2;spage=56;epage=61;aulast=Wang

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http://www.jglioma.com/article.asp?issn=2589-6113;year=2022;volume=5;issue=2;spage=56;epage=61;aulast=Wang

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