A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer

A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer

Background: Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive phenotype of breast cancer with associated chemoresistance. The development of chemo- or radioresistance could be attributed to diverse tumor microenvironments, overexpression of membrane proteins (transporters), epigene...

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Bibliographic Details
Main Authors: Hitesh Kumar, N. Vishal Gupta, Rupshee Jain, SubbaRao V. Madhunapantula, C. Saravana Babu, Siddharth S. Kesharwani, Surajit Dey, Vikas Jain
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Advanced Research
Subjects:
Triple-negative breast cancer (TNBC)
Chemoresistance
Cancer stem cells
Epigenetics
Tumor microenvironment
Therapeutic modality
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123223000565

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http://www.sciencedirect.com/science/article/pii/S2090123223000565

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