Bioinformatic Prioritization and Functional Annotation of GWAS-Based Candidate Genes for Primary Open-Angle Glaucoma

Bioinformatic Prioritization and Functional Annotation of GWAS-Based Candidate Genes for Primary Open-Angle Glaucoma

Background: Primary open-angle glaucoma (POAG) is the most prevalent glaucoma subtype, but its exact etiology is still unknown. In this study, we aimed to prioritize the most likely ‘causal’ genes and identify functional characteristics and underlying biological pathways of POAG candidate genes. Met...

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Bibliographic Details
Main Authors: Nigus G. Asefa, Zoha Kamali, Satyajit Pereira, Ahmad Vaez, Nomdo Jansonius, Arthur A. Bergen, Harold Snieder
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Genes
Subjects:
primary open angle glaucoma
GWAS
DNA methylation
gene expression
functional enrichment
Online Access:https://www.mdpi.com/2073-4425/13/6/1055

Internet

https://www.mdpi.com/2073-4425/13/6/1055

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