Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

Inhibitory G alpha (GNAI or Gαi) proteins are critical for the polarized morphogenesis of sensory hair cells and for hearing. The extent and nature of their actual contributions remains unclear, however, as previous studies did not investigate all GNAI proteins and included non-physiological approac...

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Bibliographic Details
Main Authors: Amandine Jarysta, Abigail LD Tadenev, Matthew Day, Barry Krawchuk, Benjamin E Low, Michael V Wiles, Basile Tarchini
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-04-01
Series:eLife
Subjects:
inner ear
hair cell
G proteins
cell polarity
planar polarity
hearing
Online Access:https://elifesciences.org/articles/88186

Internet

https://elifesciences.org/articles/88186

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