Impact of Sacubitril/Valsartan on surfactant binding proteins, central sleep apneas, lung function tests and heart failure biomarkers: Hemodynamic or pleiotropism?

Impact of Sacubitril/Valsartan on surfactant binding proteins, central sleep apneas, lung function tests and heart failure biomarkers: Hemodynamic or pleiotropism?

PurposeLittle is known about the mechanism underlying Sacubitril/Valsartan effects in patients with heart failure (HFrEF). Aim of the study is to assess hemodynamic vs. non-hemodynamic Sacubitril/Valsartan effects by analyzing several biological and functional parameters.MethodsSeventy-nine patients...

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Bibliographic Details
Main Authors: Massimo Mapelli, Irene Mattavelli, Elisabetta Salvioni, Cristina Banfi, Stefania Ghilardi, Fabiana De Martino, Paola Gugliandolo, Valentina Mantegazza, Valentina Volpato, Christian Basile, Maria Inês Fiuza Branco Pires, Valentina Sassi, Benedetta Nusca, Carlo Vignati, Mauro Contini, Chiarella Sforza, Maria Luisa Biondi, Pasquale Perrone Filardi, Piergiuseppe Agostoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Sacubitril/Valsartan
heart failure
surfactant binding proteins
biomarkers
hemodynamics
pleiotropic
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.971108/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.971108/full

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