TACSTD2 upregulation is an early reaction to lung infection

Abstract TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody–drug conjugate targeting Trop2 were recently approved for cancer therapy, the physiological role of Trop2 is still not fully und...

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Bibliographic Details
Main Authors: Sára Lenárt, Peter Lenárt, Lucia Knopfová, Hana Kotasová, Vendula Pelková, Veronika Sedláková, Ondřej Vacek, Jana Pokludová, Vladimír Čan, Jan Šmarda, Karel Souček, Aleš Hampl, Petr Beneš
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13637-9