Chronic exposure to aflatoxin B1 increases hippocampal microglial pyroptosis and vulnerability to stress in mice

Chronic exposure to aflatoxin B1 increases hippocampal microglial pyroptosis and vulnerability to stress in mice

Background: Chronic aflatoxin B1 (AFB1) exposure may increase the risk of multiple neuropsychiatric disorders. Stress is considered one of the main contributors to major depressive disorder. Whether and how chronic AFB1 exposure affects vulnerability to stress is unclear. Methods: Mice were exposed...

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Bibliographic Details
Main Authors: Dapeng Su, Weike Jiang, Qingsong Yuan, Lanping Guo, Qin Liu, Mengmeng Zhang, Chuangzhi Kang, Chenghong Xiao, Changgui Yang, Liangyuan Li, Chunyun Xu, Tao Zhou, Jinqiang Zhang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Stress vulnerability
Aflatoxin B1
Microglial pyroptosis
NLRP3
Neurogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323004955

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http://www.sciencedirect.com/science/article/pii/S0147651323004955

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