Sequence–Activity Relationship of ATCUN Peptides in the Context of Alzheimer’s Disease

Amino-terminal Cu<sup>II</sup> and Ni<sup>II</sup> (ATCUN) binding sequences are widespread in the biological world. Here, we report on the study of eight ATCUN peptides aimed at targeting copper ions and stopping the associated formation of reactive oxygen species (ROS). Thi...

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Bibliographic Details
Main Authors: Margot Lefèvre, Kyangwi P. Malikidogo, Charlène Esmieu, Christelle Hureau
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/22/7903