Measurement of 8‐hydroxy‐2′‐deoxyguanosine in serum and cerebrospinal fluid of horses with neuroaxonal degeneration and other causes of proprioceptive ataxia

Measurement of 8‐hydroxy‐2′‐deoxyguanosine in serum and cerebrospinal fluid of horses with neuroaxonal degeneration and other causes of proprioceptive ataxia

Abstract Background Eight‐hydroxy‐2′‐deoxyguanosine (8‐OHdG), a biomarker of oxidative damage evaluated in human neurodegenerative disease, has potential to correlate with postmortem diagnosis of neuroaxonal dystrophy/degenerative myeloencephalopathy (NAD/DM) in horses. Hypothesis We hypothesized th...

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Bibliographic Details
Main Authors: Megan Palmisano, Jeaneen Kulp, Susan Bender, Darko Stefanovski, Mary Robinson, Amy Johnson
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Journal of Veterinary Internal Medicine
Subjects:
ataxia
equine degenerative myeloencephalopathy (EDM)
equine neuroaxonal dystrophy (eNAD)
neurodegenerative
oxidative damage
Online Access:https://doi.org/10.1111/jvim.16988

Internet

https://doi.org/10.1111/jvim.16988

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